Article

De novo design of a peptide ligand for specific affinity purification of human complement C1q

2026-04-01

Abstract excerpt

Affinity purification is a essential technique for isolating highly purified proteins; however, generating affinity ligands require significant time and financial investment. To address these limitations, this study proposes a novel affinity chromatography method utilizing in silico -designed cyclic peptides as ligands. Targeting Complement C1q (C1q), a plasma protein that plays crucial roles in classical complem...

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Literature Corpus work: f601869c-4838-50d0-9f04-2f4e9061525e
DOI: 10.64898/2026.03.30.714096

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