Article

Single-cell transcriptomic and TCR analysis of human Cytomegalovirus (hCMV)-specific memory T cells reveals effector and pre-effectors of CD8 + - and CD4 + -cytotoxic T cells

2023-10-15

Abstract excerpt

Latent human Cytomegalovirus (hCMV) infection can pose a serious threat of reactivation and disease occurrence in immune-compromised individuals. Though, T cells are at the core of the protective immune response to hCMV infection, a detailed characterization of different T cell subsets involved in hCMV immunity is lacking. Here, in an unbiased manner, we characterized over 8000 hCMV-reactive peripheral memory T ce...

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Literature Corpus work: f5f9ef8a-24f5-5cac-bfc2-718137169ac1
DOI: 10.22541/au.169735638.81514076/v1

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