Article
Deep Profiling of the CD8+ T-cell Compartment Identifies Activated Cell Subsets and Multifunctional Responses Associated With Control of Cytomegalovirus Viremia.
Transplantation - 1 Mar 2019
Ferreira Victor H, Kumar Deepali, Humar Atul
Abstract excerpt
BACKGROUND: Human cytomegalovirus (HCMV) is a common opportunistic pathogen in transplant recipients. Patterns of viremia and reactivation are influenced by the host immune response, including CD8 T cells. However, the cellular deficits or phenotypic differences that account for differential outcomes during HCMV viremia are incompletely understood. METHODS: Peripheral blood mononuclear cells were collected from...
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