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Single-cell transcriptomic and TCR analysis of human Cytomegalovirus (hCMV)-specific memory T cells reveals effector and pre-effectors of CD8 <sup>+</sup> - and CD4 <sup>+</sup> -cytotoxic T cells

2023-06-05

Abstract excerpt

<h4>Background</h4> Latent human Cytomegalovirus (hCMV) infection can pose a serious threat of reactivation and disease occurrence in immune-compromised individuals. Though, T cells are at the core of the protective immune response to hCMV infection, a detailed characterization of different T cell subsets involved in hCMV immunity is lacking. <h4>Results</h4> Here, in an unbiased manner, we characterized over 80...

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Literature Corpus work
ceaea95e-ee37-563f-86ce-7cfc555d4edd
DOI
10.1101/2023.06.02.543443
Open publication

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Single-cell transcriptomic and TCR analysis of human Cytomegalovirus (hCMV)-specific memory T cells reveals effector and pre-effectors of CD8 <sup>+</sup> - and CD4 <sup>+</sup> -cytotoxic T cellsDOI 10.1101/2023.06.02.543443
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