Article

Regional Mutational Signature Activities in Cancer Genomes

2022-01-24

Abstract excerpt

Cancer genomes harbor a catalog of somatic mutations. The type and genomic context of these mutations depend on their causes, and allow their attribution to particular mutational signatures. Previous work has shown that mutational signature activities change over the course of tumor development, but investigations of genomic region variability in mutational signatures have been limited. Here, we expand upon this w...

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Literature Corpus work: fa63631e-f86f-5ec8-8992-6b829cc8a03c
DOI: 10.1101/2022.01.23.477261

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