Article

Visualizing the dynamics of ionotropic glutamate receptors using atomic force microscopy

2017-01-01

Abstract excerpt

Glutamate is the major excitatory neurotransmitter in the mammalian brain. It binds to three different subclasses of ionotropic glutamate receptors (iGluRs): AMPA, kainate and NMDA receptors, and triggers a cation influx that generates synaptic currents crucial to brain function. Significantly, iGluRs are implicated in various neurological disorders, such as depression, schizophrenia, Alzheimer’s and Parkinson’s d...

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Literature Corpus work: f5de0c11-75bd-5433-a234-9d4769d92bfe
DOI: 10.17863/cam.15240

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