Measurements of the Timescale and Conformational Space of AMPA Receptor Desensitization.

doi:10.1016/j.bpj.2020.05.029

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Measurements of the Timescale and Conformational Space of AMPA Receptor Desensitization.

Biophysical journal - 7 Jul 2020

Salazar Hector, Mischke Sabrina, Plested Andrew J R

Abstract excerpt

Ionotropic glutamate receptors are ligand-gated ion channels that mediate excitatory synaptic transmission in the central nervous system. Desensitization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid subtype after glutamate binding appears critical for brain function and involves rearrangement of the ligand binding domains (LBDs). Recently, several full-length structures of ionotropic glutamate...

Topics

Mutation
Protein Domains
Receptors, AMPA
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 32559412
DOI: 10.1016/j.bpj.2020.05.029
PMCID: PMC7335938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics