Article

The expression patterns of different cell types and their interactions in the tumor microenvironment are predictive of breast cancer patient response to neoadjuvant chemotherapy

2024-06-25

Abstract excerpt

<title>Abstract</title> <p>The tumor microenvironment (TME) is a complex ecosystem of diverse cell types whose interactions govern tumor growth and clinical outcome. While the TME’s impact on immunotherapy has been extensively studied, its role in chemotherapy response remains less explored. To address this, we developed DECODEM (DEcoupling Cell-type-specific Outcomes using DEconvolution and Machine learning), a...

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Literature Corpus work: f5bad176-fe9e-59d7-a341-f9bdd6c7d596
DOI: 10.21203/rs.3.rs-4583538/v1

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