Article

Explainable Machine Learning Reveals the Role of the Breast Tumor Microenvironment in Neoadjuvant Chemotherapy Outcome

2023-09-10

Abstract excerpt

Recent advancements in single-cell RNA sequencing (scRNA-seq) have enabled the identification of phenotypic diversity within breast tumor tissues. However, the contribution of these cell phenotypes to tumor biology and treatment response has remained less understood. This is primarily due to the limited number of available samples and the inherent heterogeneity of breast tumors. To address this limitation, we leve...

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Literature Corpus work: c6a65381-874d-53d9-8ce4-78ab55980219
DOI: 10.1101/2023.09.07.556655

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