Article

Enhanced prediction of breast cancer patient response to chemotherapy by integrating deconvolved expression patterns of immune, stromal and tumor cells

2024-06-14

Abstract excerpt

<h4>ABSTRACT</h4> The tumor microenvironment (TME) is a complex ecosystem of diverse cell types whose interactions govern tumor growth and clinical outcome. While multiple studies have extensively charted the TME’s impact on immunotherapy, its role in chemotherapy response remains less explored. To address this, we developed DECODEM ( DE coupling C ell-type-specific O utcomes using DE convolution and M achin...

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Literature Corpus work: 14fc27da-78b5-5de0-8109-cab15fde1c3b
DOI: 10.1101/2024.06.14.598770

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