Article

CellTFusion: a transcriptional regulatory network framework for the identification of functional multicellular states from bulk RNA-seq data

2026-07-05

Abstract excerpt

Bulk RNA-seq remains the most accessible transcriptomic platform for tumor microenvironment (TME) characterization, yet existing computational approaches treat cell type abundance, pathway activity, and transcription factor (TF) activity as independent sources of information, missing the coordinated regulatory programs that define functional multicellular states. Here we introduce CellTFusion, a framework that int...

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Literature Corpus work: 7f916d79-8830-5691-a615-73ab3e7558b8
DOI: 10.64898/2026.06.30.735682

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