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Multi-omics analyses of the heterogenous immune microenvironment in triple-negative breast cancer implicate UQCRFS1 potentiates tumor progression

16 Jun 2025

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Abstract Background Triple-negative breast cancer (TNBC) is commonly characterized by high-grade and aggressive features, resulting in an augmented likelihood of distant metastasis and inferior prognosis for patients. Tumor immune microenvironment (TME) has been recently considered to be tightly correlated with tumor progression and immunotherapy response. However, the actual heterogenous TME within TNBC remains...

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Cancer Immunotherapy and Biomarkers
Ferroptosis and cancer prognosis
Single-cell and spatial transcriptomics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40524231
DOI: 10.1186/s40164-025-00672-1

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