Article

The microglia receptor protein TREM2 is essential for protective innate immune responses against herpesvirus infection in the brain

2023-03-16

Abstract excerpt

Immunological control of viral infection in the brain is essential for immediate protection, but also for long-term maintenance of brain integrity. As the primary resident immune cell of the brain, microglia protect against viral infections through key macrophage functions, including release of the antiviral type I interferons (IFN-I) and clearance of infected cells. Microglia express the cytosolic DNA sensor cycl...

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Literature Corpus work: f5b11265-ab9a-562d-b404-ca69cfb77001
DOI: 10.1101/2023.03.16.532882

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