Article

Functional apoptosis profiling reveals vulnerabilities in T-cell large granular lymphocytic leukemia

2023-11-20

Abstract excerpt

T-cell large granular lymphocytic leukemia (T-LGL) is a rare hematologic neoplasm characterized by clonal expansion of CD3+ cytotoxic T lymphocytes and a highly heterogeneous clinical course. Conventional therapy primarily includes immunosuppressive regimen. However, optimal front-line approaches still need to be defined and refractory disease remains a clinical challenge. Thus, we here aimed to explore functional...

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Literature Corpus work: f5a62a03-59a8-520a-a91f-8822fb2dd9a6
DOI: 10.21203/rs.3.rs-3619733/v1

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