Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T-large granular lymphocytic leukemia

7 Apr 2023

Abstract excerpt

T-cell large granular lymphocyte (T-LGL) leukemia is characterized by clonal expansion of cytotoxic T cells resulting in cytopenia. The proliferation of clonal LGLs is caused by prolonged antigenic stimulation, which leads to apoptotic dysregulation owing mainly to the constitutive activation of survival pathways, notably the JAK/STAT pathway. Understanding how leukemic T-LGL persists can aid in the development...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to Immune Cell Function and Interaction
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37026382
DOI: 10.5045/br.2023.2023037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T-large granular lymphocytic leukemiaPMID 37026382Read ↗

Large granular lymphocytic leukemia. Current diagnostic and therapeutic approaches and novel treatment options.Semantic proximity Read ↗

Large granular lymphocyte leukemia: a clonal disorder with autoimmune manifestations.Semantic proximity Read ↗

Insights Into Genetic Landscape of Large Granular Lymphocyte LeukemiaSemantic proximity Read ↗

Clinical features and treatment outcomes in large granular lymphocytic leukemia (LGLL).Semantic proximity Read ↗

A modern view of LGL leukemia.Semantic proximity Read ↗

Not all LGL leukemias are created equal.Semantic proximity Read ↗

T-cell and natural killer-cell large granular lymphocyte leukemia neoplasiasSemantic proximity Read ↗

Large granular lymphocyte leukemia.Semantic proximity Read ↗

[Large Granular Lymphocytic Leukemia and JAK/STAT Signaling Pathway--Review].Semantic proximity Read ↗

Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia.Semantic proximity Read ↗

Flow cytometric analysis of phenotypes and naïve/memory/effector T-cell subsets of T-cell large granular lymphocytic leukemia.Semantic proximity Read ↗

Diagnosis and Management of Large Granular Lymphocytic Leukaemia and Its Differentiation From T Cell Clones of Uncertain SignificanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.