Article
STAT3 mutation and its clinical and histopathologic correlation in T-cell large granular lymphocytic leukemia.
Human pathology - 1 Mar 2018
Shi Min, He Rong, Feldman Andrew L, Viswanatha David S, Jevremovic Dragan, Chen Dong, Morice William G
Abstract excerpt
Although T-cell large granular lymphocytic leukemia (T-LGLL) is a clinically indolent disorder, patients with moderate to severe cytopenia require therapeutic intervention. The recent discovery of STAT3 mutations has shed light on the genetic basis of T-LGLL pathogenesis. However, the association of STAT3 mutational status with patients' clinical, histopathologic, and other laboratory features has not been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.