Article
DNA motif analysis of shear stress responsive endothelial enhancers reveals differential association of KLF and ETV/ETS binding sites with gained and lost enhancers
2021-09-21
Abstract excerpt
Endothelial cells (EC) lining blood vessels are exposed to mechanical forces, such as shear stress exerted by the flowing blood. These forces control many aspects of EC biology, including vascular tone, cell migration and proliferation in addition to cell size and shape. Despite a good understanding of the genes and signaling pathways responding to shear stress, our insights into the transcriptional regulation of...
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Identifiers and source
- Literature Corpus work
- f57ac52d-8935-5bff-bdbe-dfe73fc73746
- DOI
- 10.1101/2021.09.21.460846
