Article

HLA Allele Imputation with Multitask Deep Convolutional Neural Network

2021-06-05

Abstract excerpt

<h4>Motivation</h4> The Human leukgocyte antigen (HLA) system is a highly polymorphic gene complex encoding the major histocompatibility complex proteins in humans. HLA alleles are of strong epidemiological interest for their large effect sizes in associations with autoimmune diseases, infectious diseases, severe drug reactions, and transplant medicine. Since HLA genotyping can be time-consuming and cost-prohibit...

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Literature Corpus work: f574eef9-4ec7-515d-bd61-cef4963e2130
DOI: 10.1101/2021.06.03.447012

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