Article
HIBAG--HLA genotype imputation with attribute bagging.
The pharmacogenomics journal - 1 Apr 2014
Zheng X, Shen J, Cox C, Wakefield J C, Ehm M G, Nelson M R, Weir B S
Abstract excerpt
Genotyping of classical human leukocyte antigen (HLA) alleles is an essential tool in the analysis of diseases and adverse drug reactions with associations mapping to the major histocompatibility complex (MHC). However, deriving high-resolution HLA types subsequent to whole-genome single-nucleotide polymorphism (SNP) typing or sequencing is often cost prohibitive for large samples. An alternative approach takes...
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