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Multiomics Evaluation of Human iPSCs and iPSC-Derived Neurons

28 Feb 2024

Abstract excerpt

Human induced pluripotent stem cells (iPSCs) can be differentiated into neurons, providing living human neurons to model brain diseases. However, it is unclear how different types of molecules work together to regulate stem cell and neuron biology in healthy and disease states. In this study, we conducted integrated proteomics, lipidomics, and metabolomics analyses with confident identification, accurate...

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PMID: 38415376
DOI: 10.1021/acs.jproteome.3c00790

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