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Article

Improved architectures for flexible DNA production using retrons across kingdoms of life

2021-03-26

Abstract excerpt

<h4>ABSTRACT</h4> Exogenous DNA is a critical molecular tool for biology. This is particularly true for gene editing, where exogenous DNA can be used as a template to introduce precise changes to the sequence of a cell’s genome. This DNA is typically synthesized or assembled in vitro and then delivered to target cells. However, delivery can be inefficient, and low abundance of template DNA may be one reason that...

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Literature Corpus work
f5629f58-bce3-5ced-8533-3f226265d7b9
DOI
10.1101/2021.03.26.437017
Open publication

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Improved architectures for flexible DNA production using retrons across kingdoms of lifeDOI 10.1101/2021.03.26.437017
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