Article

Continuous Multiplexed Phage Genome Editing Using Recombitrons

2023-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Bacteriophages, which naturally shape bacterial communities, can be co-opted as a biological technology to help eliminate pathogenic bacteria from our bodies and food supply 1 . Phage genome editing is a critical tool to engineer more effective phage technologies. However, editing phage genomes has traditionally been a low efficiency process that requires laborious screening, counter selection,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5341c70e-a68c-5afb-8e41-225153abf9bb
DOI: 10.1101/2023.03.24.534024

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Continuous Multiplexed Phage Genome Editing Using RecombitronsDOI 10.1101/2023.03.24.534024Read

RNA and Single-Stranded DNA Phages: Unveiling the Promise from the Underexplored World of VirusesSemantic proximity Read

Phage defense and genome editing using novel retrons sourced from isolated environmental bacteriaSemantic proximity Read

Engineered Bacteriophages: Advances in Phage Genome Redesign Strategies for Therapeutic and Environmental ApplicationsSemantic proximity Read

Engineered bacteriophages: A panacea against pathogenic and drug resistant bacteriaSemantic proximity Read

Engineered Bacteriophages: A Panacea Against Pathogenic and Drug Resistant BacteriaSemantic proximity Read

Synthetic and Functional Engineering of Bacteriophages: Approaches for Tailored Bactericidal, Diagnostic, and Delivery PlatformsSemantic proximity Read

High-throughput functional variant screens via in vivo production of single-stranded DNA.Semantic proximity Read

Synthetic and Functional Engineering of Bacteriophages: Approaches for Tailored Bactericidal, Diagnostic, and Delivery PlatformsSemantic proximity Read

An efficient, scarless, selection-free technology for phage engineering.Semantic proximity Read

Manipulating replisome dynamics to enhance lambda Red-mediated multiplex genome engineering.Semantic proximity Read

Improving lambda red genome engineering in Escherichia coli via rational removal of endogenous nucleases.Semantic proximity Read

Genetic engineering of bacteriophages: Key concepts, strategies, and applicationsSemantic proximity Read