Article

Transcriptional and clonal characterization of cytotoxic CD8 <sup>+</sup> T cells in crescentic glomerulonephritis

2022-09-02

Abstract excerpt

Crescentic glomerulonephritis (cGN), most often caused by anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis, is an aggressive form of immune-mediated kidney disease and represents an important cause of end-stage renal failure. Although it is known that T cells infiltrate the kidney in cGN, their precise role in autoimmune kidney disease remains to be fully elucidated. By performing single-cell...

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Literature Corpus work: f4ec73a7-be02-5fa0-a50d-0855b60de75f
DOI: 10.1101/2022.08.31.506004

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