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Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis

2024-05-17

Abstract excerpt

<title>Abstract</title> <p>Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis is a life-threatening autoimmune disease that often results in kidney failure caused by crescentic glomerulonephritis (ANCA-GN). To date, treatment of most patients with ANCA-GN relies on unspecific immunosuppressive agents that harbor serious adverse effects and are sometimes only partially effective. By performing spatia...

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Literature Corpus work
15d69cc8-b060-5374-9e8a-f58ba623fb73
DOI
10.21203/rs.3.rs-4425161/v1
Open publication

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Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritisDOI 10.21203/rs.3.rs-4425161/v1
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