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Article

Tumor infiltrating lymphocytes in seminoma lesions comprise clonally expanded cytotoxic T cells.

International journal of cancer - 15 Aug 2006

Hadrup Sine Reker, Braendstrup Otto, Jacobsen Grete Krag, Mortensen Svend, Pedersen Lars Østergaard, Seremet Tina, Andersen Mads Hald, Becker Jürgen C, Straten Per Thor

Abstract excerpt

Seminoma lesions are characterized by a brisk inflammatory infiltrate containing both CD4 and CD8 T cells, which is of prognostic significance. However, whether seminoma cells express the HLA molecules required for classical T-cell recognition remains controversial. In the present study, we conducted a molecular, phenotypical and functional characterization of tumor infiltrating lymphocytes (TILs) from seminoma...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16557580
DOI: 10.1002/ijc.21894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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