Article
CD4-positive effector memory T cells participate in disease expression in ANCA-associated vasculitis.
Annals of the New York Academy of Sciences - 1 Jun 2007
Abdulahad Wayel H, Stegeman Coen A, Limburg Pieter C, Kallenberg Cees G M
Abstract excerpt
Although the cause of ANCA-associated vasculitis (AAV) remains undetermined, the presence of lymphocytic infiltrates in inflammatory lesions of patients suggests that vascular damage is immune mediated. Studies over the past decade have implicated a role for T cells in the pathogenesis of AAV as altered T cell phenotype has been observed in this disorder. The distribution of T cell subpopulations has been...
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