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The Liver-Enriched Long Non-Coding RNA FAM99A Suppresses Tumorigenesis through Negative Regulation of Protein Synthesis

2025-05-04

Abstract excerpt

<h4>ABSTRACT</h4> Primary liver cancer represents a significant global health burden, with limited therapeutic options for advanced disease. Long non-coding RNAs (lncRNAs) are increasingly found to play crucial roles in hepatic biology and disease progression. Here, we identify FAM99A as a highly liver-specific lncRNA that is systematically downregulated across liver malignancies, with reduced expression correlat...

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Literature Corpus work
f4c4bb8d-1dcc-595f-afc0-6d82d3ee0f62
DOI
10.1101/2025.04.29.651319
Open publication

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The Liver-Enriched Long Non-Coding RNA FAM99A Suppresses Tumorigenesis through Negative Regulation of Protein SynthesisDOI 10.1101/2025.04.29.651319
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