Article

PHAROH lncRNA regulates c-Myc translation in hepatocellular carcinoma via sequestering TIAR

2021-03-23

Abstract excerpt

Hepatocellular carcinoma, the most common type of liver malignancy, is one of the most lethal forms of cancer. We identified a long non-coding RNA, Gm19705, that is overexpressed in hepatocellular carcinoma and mouse embryonic stem cells. We named this RNA Pluripotency and Hepatocyte Associated RNA Overexpressed in HCC, or PHAROH. Depletion of PHAROH impacts cell proliferation and migration, which can be rescued b...

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Literature Corpus work: 9e3dd67a-7aae-55cc-9f26-ee8a71bf77d6
DOI: 10.1101/2021.03.23.436634

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