Ribosome profiling reveals extensive translational alterations in steatohepatitis-associated hepatocellular carcinoma

Abstract excerpt

Hepatocellular carcinoma (HCC) is one the most lethal cancer types. While infections with hepatitis B or hepatitis C viruses remain the primary risk factors for HCC development worldwide, metabolic disease-associated steatohepatitis has become the fastest growing etiology of HCC, particularly in the West. Our study characterizes, for the first time, the remodeling of the translation landscape in steatohepatitis-as...

Topics

Open a Topic to create a Post that cites this publication.

• Diet, Metabolism, and Disease
• Endoplasmic Reticulum Stress and Disease
• Gene Expression Regulation, Neoplastic
• Genetic Predisposition to Disease
• Neoplasms
• Protein Biosynthesis
• RNA and protein synthesis mechanisms
• RNA modifications and cancer

Identifiers and source

Literature Corpus work

ac8f70ac-2249-5ed3-bc0b-b30bb9fbd9cd

DOI

10.64898/2026.02.11.705272