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Article

EIF4A3: a gatekeeper of autophagy

13 Oct 2021

Abstract excerpt

EIF4A3 (eukaryotic translation initiation factor 4A3) is an RNA helicase and core component of the exon junction complex. While this RNA-binding protein (RBP) is well-characterized for its crucial roles in splicing, RNA trafficking and nonsense-mediated decay, its role in the regulation of metabolic signaling pathways remains elusive. In a recent study, we describe a new role for EIF4A3 as a negative regulator of...

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PMID: 34643458
DOI: 10.1080/15548627.2021.1985881

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