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Article

High-throughput analysis of ANRIL circRNA isoforms in human pancreatic islets

2022-01-04

Abstract excerpt

<h4>ABSTRACT</h4> The a ntisense n on-coding R NA in the I NK l ocus (ANRIL) is a hotspot for genetic variants associated with cardiometabolic disease. We recently found increased ANRIL abundance in human pancreatic islets from donors with certain Type II Diabetes (T2D) risk-SNPs, including a T2D risk-SNP located within ANRIL exon 2 associated with beta cell proliferation. Recent studies have found that expr...

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Literature Corpus work
f48c6007-2459-5e14-8ec4-d3a7e416c05b
DOI
10.1101/2022.01.03.474854
Open publication

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High-throughput analysis of ANRIL circRNA isoforms in human pancreatic isletsDOI 10.1101/2022.01.03.474854
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