Article
A landscape of circular RNA expression in the human heart.
Cardiovascular research - 1 Mar 2017
Tan Wilson L W, Lim Benson T S, Anene-Nzelu Chukwuemeka G O, Ackers-Johnson Matthew, Dashi Albert, See Kelvin, Tiang Zenia, Lee Dominic Paul, Chua Wee Woon, Luu Tuan D A, Li Peter Y Q, Richards Arthur Mark, Foo Roger S Y
Abstract excerpt
Aims: Circular RNA (circRNA) is a newly validated class of single-stranded RNA, ubiquitously expressed in mammalian tissues and possessing key functions including acting as microRNA sponges and as transcriptional regulators by binding to RNA-binding proteins. While independent studies confirm the expression of circRNA in various tissue types, genome-wide circRNA expression in the heart has yet to be described in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.