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Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells

18 Mar 2025

Abstract excerpt

Abstract Aims/hypothesis MiRNAs regulate gene expression, influencing beta cell function and pathways. Isoforms of miRNA (isomiRs), sequence variants of miRNAs with post-transcriptional modifications, exhibit cell-type-specific expression and functions. Despite their biological significance, a comprehensive isomiR profile in human pancreatic islets and beta cells remains unexplored. This study aims to profile...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40102237
DOI: 10.1007/s00125-025-06397-4

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