Article
A map of human circular RNAs in clinically relevant tissues.
Journal of molecular medicine (Berlin, Germany) - 1 Nov 2017
Maass Philipp G, Glažar Petar, Memczak Sebastian, Dittmar Gunnar, Hollfinger Irene, Schreyer Luisa, Sauer Aisha V, Toka Okan, Aiuti Alessandro, Luft Friedrich C, Rajewsky Nikolaus
Abstract excerpt
Cellular circular RNAs (circRNAs) are generated by head-to-tail splicing and are present in all multicellular organisms studied so far. Recently, circRNAs have emerged as a large class of RNA which can function as post-transcriptional regulators. It has also been shown that many circRNAs are tissue- and stage-specifically expressed. Moreover, the unusual stability and expression specificity make circRNAs...
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