Article

Prior hypoxia exposure enhances murine microglial inflammatory gene expression <i>in vitro</i> without concomitant H3K4me3 enrichment

2020-02-04

Abstract excerpt

<h4>ABSTRACT</h4> Hypoxia is a component of multiple disorders, including stroke and sleep-disordered breathing, that often precede or are comorbid with neurodegenerative diseases. However, little is known about how hypoxia affects the ability of microglia, resident CNS macrophages, to respond to subsequent inflammatory challenges that are often present during neurodegenerative processes. We therefore tested the...

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Literature Corpus work: f486d6dc-b3f9-5755-a33a-06deebd7c822
DOI: 10.1101/2020.02.03.933028

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