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The lncRNA <i>Gm16685</i> / <i>MITA1</i> modulates inflammatory astrocyte reactivity through PCBP2 associated regulation of IKKβ signaling

2026-07-09

Abstract excerpt

Long non-coding RNAs (lncRNAs) are increasingly recognized as regulators of cellular identity and disease associated gene expression programs, yet their role in astrocyte reactivity remains poorly understood. Here, we profiled lncRNA expression in primary mouse astrocytes exposed to inflammatory activation paradigms that model microglia driven signaling. This identified a conserved set of activation responsive lnc...

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Literature Corpus work
4b5ff007-05f7-5d42-9b72-ed00bd5d5b6b
DOI
10.64898/2026.07.03.736437
Open publication

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The lncRNA <i>Gm16685</i> / <i>MITA1</i> modulates inflammatory astrocyte reactivity through PCBP2 associated regulation of IKKβ signalingDOI 10.64898/2026.07.03.736437
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