Article
The Essential Genome of Burkholderia cenocepacia H111.
Journal of bacteriology - 15 Nov 2017
Higgins Steven, Sanchez-Contreras Maria, Gualdi Stefano, Pinto-Carbó Marta, Carlier Aurélien, Eberl Leo
Abstract excerpt
The study of the minimum set of genes required to sustain life is a fundamental question in biological research. Recent studies on bacterial essential genes suggested that between 350 and 700 genes are essential to support autonomous bacterial cell growth. Essential genes are of interest as potential new antimicrobial drug targets; hence, our aim was to identify the essential genome of the cystic fibrosis (CF)...
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