Article

Anoctamin 9/TMEM16J is a Cation Channel Activated by cAMP/PKA Signal

2017-09-13

Abstract excerpt

<h4>ABSTRACT</h4> Anoctamins are membrane proteins that consist of 10 homologs. ANO1 and ANO2 are anion channels activated by intracellular calcium that meditate numerous physiological functions. ANO6 is a scramblase that redistributes phospholipids across the cell membrane. However, the others are not well characterized. We found ANO9/TMEM16J is a cation channel activated by a cAMP-dependent PKA. Intracellular c...

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Literature Corpus work: f4374423-5ed7-5469-bf55-4fadf97407ca
DOI: 10.1101/188243

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