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Article

Structure and function of TMEM16 proteins (anoctamins).

Physiological reviews - 1 Apr 2014

Pedemonte Nicoletta, Galietta Luis J V

Abstract excerpt

TMEM16 proteins, also known as anoctamins, are involved in a variety of functions that include ion transport, phospholipid scrambling, and regulation of other membrane proteins. The first two members of the family, TMEM16A (anoctamin-1, ANO1) and TMEM16B (anoctamin-2, ANO2), function as Ca2+-activated Cl- channels (CaCCs), a type of ion channel that plays important functions such as transepithelial ion transport,...

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Source

Identifiers

PMID: 24692353
DOI: 10.1152/physrev.00039.2011

Genes

ANO6
ANO1
ANO10
ANO2
ANO3
ANO5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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