Article

Nuclear biocondensate-forming lncRNA and cellular stress surveillance shape host cancer susceptibility

2021-04-27

Abstract excerpt

Host genetics is known to influence cancer susceptibility. However, the specific candidate genes and molecular mechanisms that confer resistance remain poorly understood. Here, we demonstrate the power of haploinsufficiency screen to uncover host genetic regulators of cancer in Drosophila and identify the long noncoding RNA (lncRNA) hsrω , a structural component of nuclear biomolecular condensate known as omega...

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Literature Corpus work: f4075f4b-2b5b-5d24-bfc1-d8c2d2ea41ae
DOI: 10.1101/2021.04.26.441543

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