Article

mRNA structural dynamics shape Argonaute-target interactions

2019-10-30

Abstract excerpt

Small RNAs (such as miRNAs, siRNAs and piRNAs) regulate protein expression in a wide variety of biological processes and play an important role in cellular function, development and disease. Association of small RNAs with Argonaute (AGO) family proteins guide AGO to target RNAs, generally resulting in target silencing through transcriptional silencing, translational repression or mRNA degradation. Here we develop...

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Literature Corpus work: f3eea917-7a5a-55bb-8a57-24c8af276bf5
DOI: 10.1101/822452

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