Article

Genome-wide RNA structure changes during human neurogenesis drive gene regulatory networks

2021-08-02

Abstract excerpt

The distribution, dynamics and function of RNA structures in human development is under- explored. Here, we systematically assayed RNA structural dynamics and its relationship with gene expression, translation and decay during human neurogenesis. We observed that the human ESC transcriptome is globally more structurally accessible than that of differentiated cells; and undergo extensive RNA structure changes, part...

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Literature Corpus work: f1af942a-4c39-5b31-b045-c0abe532134d
DOI: 10.1101/2021.08.02.454835

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