Article

A systematic screen of breast cancer patients’ exomes for retrotransposon insertions reveals disease associated genes

2020-06-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Retrotransposons are genetic elements that jump within the genome via an RNA intermediate. Although they had a strong impact on human genome evolution, only a very tiny fraction of them can be reactivated nowadays, most often with neutral or detrimental consequences. The pathological outcomes associated with such genetic alterations are poorly investigated in the clinic, mer...

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Literature Corpus work: f3df0361-6fca-5837-b9d3-dccb3c372bd4
DOI: 10.1101/2020.06.04.123240

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