Article

Somatic point mutations are enriched in long non-coding RNAs with possible regulatory function in breast cancer

2021-09-07

Abstract excerpt

Non-coding RNAs (ncRNAs) form a large portion of the mammalian genome however, their biological functions are poorly characterized in cancers. In this study, using a newly developed tool, SomaGene, we analyze de novo somatic point mutations from the International Cancer Genome Consortium (ICGC) whole-genome sequencing data of 1,855 breast cancers. We identify 929 candidates of ncRNAs that are significantly and exp...

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Literature Corpus work: c26fd679-1502-5316-a072-16eb1986ec74
DOI: 10.21203/rs.3.rs-827525/v1

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