Article

17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with <i>LRRC37A/2</i> expression in astrocytes

2019-11-30

Abstract excerpt

<h4>ABSTRACT</h4> Parkinson’s disease (PD) is genetically associated with the H1 haplotype of the MAPT 17q.21.31 locus, although the causal gene and variants underlying this association have not been identified. To better understand the genetic contribution of this region to PD, we fine-mapped the 17q21.31 locus in order to identify novel mechanisms conferring risk for the disease. We identified three novel H1 s...

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Literature Corpus work: f3daf36a-0596-5122-a167-0b55a41e7a8a
DOI: 10.1101/860668

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