Article

Heritability enrichment implicates microglia in Parkinson’s disease pathogenesis

2020-11-29

Abstract excerpt

<h4>Objective</h4> Understanding how different parts of the immune system contribute to pathogenesis in Parkinson’s disease is a burning challenge with important therapeutic implications. We studied enrichment of common variant heritability for Parkinson’s disease stratified by immune and brain cell types. <h4>Methods</h4> We used summary statistics from the most recent meta-analysis of genome-wide association stu...

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Literature Corpus work: 6d8ca347-ae1c-5da1-8845-8ca6914b88c9
DOI: 10.1101/2020.11.25.20238162

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