Article

Proteins as Statistical Languages: Information-Theoretic Signatures of Proteomes Across the Tree of Life

2026-01-05

Abstract excerpt

Protein sequences are commonly interpreted through biochemical and evolutionary lenses, emphasizing structure-function relationships and selection in sequence space. Here we develop a complementary viewpoint: proteins as statistical languages, strings over a finite alphabet generated by constrained stochastic processes. We formalize intrinsic informational descriptors of protein ensembles, including composition en...

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Literature Corpus work: f3d96bcb-dbbe-526f-8a5a-faee25b6c3d5
DOI: 10.64898/2025.12.31.697235

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