Article

Expansion of highly interferon-responsive T cells in early-onset Alzheimer’s disease

2023-09-27

Abstract excerpt

<h4>INTRODUCTION</h4> Altered immune signatures are emerging as a central theme in neurodegenerative disease, yet little is known about immune responses in early-onset Alzheimer’s disease (EOAD). <h4>METHODS</h4> We examined single-cell RNA-sequencing (scRNA-seq) data from peripheral blood mononuclear cells (PBMCs) and droplet digital (dd)PCR data from CD4 T cells from participants with EOAD and clinically norma...

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Literature Corpus work: f3cefc09-6482-59b5-bab8-71bbf2c14ae5
DOI: 10.1101/2023.09.26.559634

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