Article

The Peripheral Immune-Sleep- Cognition Axis Across Diagnostic Stages of Alzheimer’s Disease

2026-05-25

Abstract excerpt

<title>Abstract</title> <p> Peripheral immune dysregulation and sleep disturbances are recognized early features of Alzheimer’s disease (AD), but the mechanistic interplay between these domains is poorly understood. Here, we present a large-scale, integrated single-cell analysis of the peripheral immune landscape across the AD spectrum. We performed paired single-cell RNA sequencing (scRNA-seq) and T cell recept...

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Literature Corpus work: 45c7029a-1db1-5305-bbf9-a53dce1ce11b
DOI: 10.21203/rs.3.rs-9574288/v1

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