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ApoE ε4-dependent alteration of CXCR3 <sup>+</sup> CD127 <sup>+</sup> CD4 <sup>+</sup> T cells is associated with elevated plasma neurofilament light chain in Alzheimer’s disease

2024-06-02

Abstract excerpt

<h4>ABSTRACT</h4> Recent findings indicate a correlation between the peripheral adaptive immune system and neuroinflammation in Alzheimer’s disease (AD). To characterize the composition of adaptive immune cells in the peripheral blood of AD patients, we utilized single-cell mass cytometry (CyTOF) to profile peripheral blood mononuclear cells (PBMCs). Concurrently, we assessed the concentration of proteins associa...

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Literature Corpus work
bb141e0b-5a6a-5022-926f-9b37bd9a8402
DOI
10.1101/2024.05.28.596276
Open publication

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ApoE ε4-dependent alteration of CXCR3 <sup>+</sup> CD127 <sup>+</sup> CD4 <sup>+</sup> T cells is associated with elevated plasma neurofilament light chain in Alzheimer’s diseaseDOI 10.1101/2024.05.28.596276
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